Over the years various microprocessors have been used in many different spacecrafts. Microprocessors are used in spacecrafts are designed to be exceptionally reliable and highly durable. Because of that, often the same set of chips that have been tested and proven to work are used in many spacecrafts. Below is a list of microprocessors used in spacecrafts.

1960s

Year	Picture	Spacecraft	Description
1959-1963	200px	Mercury spacecraft	The Mercury spacecraft, NASA's first human spaceflight, had barely enough space for a single occupant. The spacecraft had no independent maneuvering capabilities - relying completely on the Atlas booster rocket. Because of that, it was unnecessary for the spacecraft to have a dedicated on-board computer. Limited functionality was done by various smaller systems.
1962-1966		Gemini Spacecraft	The Gemini Spacecraft, part of Project Gemini, NASA's second human spaceflight program, that ran from 1965-1966, carried an on-board digital computer called the Gemini Guidance Computer. The computer, which weighted fifty pounds and measured nineteen inches long, had about 19.5KB of memory.
1961-1972		Apollo spacecraft	The Apollo spacecraft, part of the Wikipedia:Apollo program, NASA's third human spaceflight program, that ran from 1961 to 1972, carried an on-board digital computer called the Apollo Guidance Computer. The 16-bit computer weighted 70 pounds and consumed 55W had a clock speed of 2.048 MHz.

1970s

Year	Picture	Spacecraft	Description
1971		Pioneer 10	The Pioneer 10, which was launched on March 3, 1972, became the first spacecraft to achieve escape velocity from the Solar System. The spacecraft's process were made of individual transistor-transistor logic chips. A common myth is that the Intel 4004 powered the Pioneer 10, this, however, incorrect.
1973		Pioneer 11	The Pioneer 11, was launched on April 6, 1973 in order to study the Asteroid belt. Just like it's twin prob, the Pioneer 10, its CPU was also a custom-designed TTL CPU.
1973		Skylab	The Skylab, which was launched on May 14, 1973, and operated until 1979, used an IBM System/4Pi model TC-1 (Tactical Computer), a miniaturized and hardened version of the IBM System/360 computers.